| COACH | HIRED | MLS RECORD | TOTAL RECORD | TROPHIES | DEPARTED |
|---|---|---|---|---|---|
| Lothar Osiander | November 29, 1995 | 22-22-0 | 26-24-0 | none | June 10, 1997 |
| Octavio Zambrano | June 10, 1997-a | 39-18-0 | 44-23-0 | none | April 22, 1999 |
| Ralph Perez | *** | 1-0-0 | 1-0-0 | none | *** |
| Sigi Schmid | April 22, 1999-b | 79-53-31 | 110-68-40 | CCC 00, USOC 01, MLS 02 | August 16, 2004 |
| Steve Sampson | August 18, 2004 | 17-24-10 | 25-27-12 | MLS 05, USOC 05 | June 6, 2006 |
| Frank Yallop | June 7, 2006 | 18-21-12 | 23-23-12 | none | November 5, 2007 |
| Ruud Gullit | November 8, 2007 | 6-8-5 | 6-9-5 | none | August 11, 2008 |
| Cobi Jones-c | August 11, 2008 | 0-0-1 | 0-0-1 | none | August 18, 2008 |
| Bruce Arena | August 18, 2008 | 125-70-79 | 166-93-89 | SS 10, SS 11, MLS 11, MLS 12, MLS 14 | November 22, 2016 |
| Curt Onalfo | December 13, 2016 | 6-10-4 | 8-11-4 | none | July 27, 2017 |
| Sigi Schmid | July 27, 2017 | 12-18-12 | 13-19-12 | none | September 10, 2018 |
| Dominic Kinnear-c | September 10, 2018 | 3-2-1 | 3-2-1 | none | January 2, 2019 |
| Guillermo Barros Schelotto | January 2, 2019 | 21-26-6 | 23-28-6 | none | October 29, 2020 |
| Dominic Kinnear-c | October 29, 2020 | 1-1-1 | 1-1-1 | none | January 5, 2021 |
| Greg Vanney | January 5, 2021 | 35-38-29 | 41-43-29 | serving |
| a-originally named interim coach; made full-time coach November 4, 1997 |
| b-hired April 22, 1999 but did not join club until one more match had been played; Ralph Perez served as interim |
| c-hired as interim coach |
| ***-coached as interim in place of Sigi Schmid who had been hired but could not immediately join the club |